Paw Pressure (Randall-Selitto test)
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Presentation
- The paw pressure test consists in applying a uniformly increasing mechanical pressure on the animal paw.
This pressure induces pain leading to an escape reaction.
- The paw pressure test consists in applying a uniformly increasing mechanical pressure on the animal paw.
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Compound testing
Pain killer or anti-inflammatory compounds are usually tested in this model but other treatments could also be considered. Please feel free to contact us to discuss the feasibility of your study.
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Endpoints
Withdrawal latency (g) in the Randall-Selitto test.
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Randall-Selitto test : Morphine dose response
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