Animal model of nerve-axonal regeneration - Newsletter - Preclinical Contract Research Organization (CRO) for CNS and PNS disorders

Animal model of peripheral neuropathy : Evaluation of nerve / axonal regeneration

Newsletter # 58

Animal models

Peripheral neuropathy is the result of a peripheral nerve injury which can be caused either by trauma, disease or drug treatment (e.g. chemotherapy). The strategies currently being developed by pharmaceutical industries for the treatment of these pathologies involve in most cases neuroprotection or even neuroregeneration.

An example of a model that can be used to evaluate the neuroregenerative efficacy of compounds is the sciatic nerve crush model which implements a unique set of readouts to better characterize the recovery from the injury.

Please note that these endpoints can also be adapted to other peripheral neuropathy models. If you are interested in discussing your project with our scientific team, please feel free to contact us.

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Allergic contact inflammation

Diabetic neuropathy

NEUROFIT offers a range of validated in vitro and in vivo screening tests for psychiatry and neurology.

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Newsletter # 58

Animal models

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NEUROFIT offers a range of validated in vitro and in vivo screening tests for psychiatry and neurology.