Newsletter # 39

Cellular models

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Example of the effect of treatment on neuritogenesis. BDNF is a brain derived neurotrophin; donepezil (Aricept®) is a centrally active small molecule used in the treatment of Alzheimer’s disease and different cognitive disorders
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Immuno-labelling of a primary neuronal culture
The blue colour represents the nucleus (DAPI staining) and the green the neuronal cytoskeleton (tubuline detection).
Bar = 100 µm -
Example of neuron scaffold detected during neuritogeneis analysis
Neuronal cytoplasm is circle in blue, neurites are outline in purple, branch point is indicated by a orange dot and red circle represents excluded object
(border line neurons for exemple)
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