Rapid, sensitive, cost effective assay for the screening of cognitive enhancer compounds

Newsletter # 21



Animal models

Screening of cognitive enhancer compounds

NEUROFIT is a Contract Research Organisation (CRO) specialising in the evaluation of treatments for peripheral and central nervous system disorders.
NEUROFIT offers a long list of in vivo and in vitro validated methods and disease models for drug screening.



  • Age-associated memory impairment (AAMI) can be measured in the mouse by a reduced spontaneous alternation in the T-maze.



  • Mouse AAMI is reversed by Donepezil (Aricept) as well as by Nicotine, suggesting at least a dysfunction in the cholinergic system.


NEUROFIT offers a range of validated in vitro and in vivo screening tests for psychiatry and neurology.

If you need further information, please do not hesitate to contact us, we will reply within few days. Custom protocol

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