In-vivo screening of antidepressant

Newsletter # 52



Animal models

In the Forced Swimming Test, immobility is interpreted as depression-like behavior (behavioral despair). Antidepressant drugs, such as Imipramine and Fluoxetine, actively perform escape-directed behaviors and thus significantly reduce immobility time.


Cost-Effective screening assay for antidepressant compounds :
Fully automated - Fast turn-around - Highly reproducible - Validated with different pathways



  • *** statistically significant as compared to the Vehicle condition



  • *, ** statistically significant as compared to the Vehicle condition


NEUROFIT offers a range of validated in vitro and in vivo screening tests for psychiatry and neurology.

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