DONEPEZIL

Newsletter # 25



Animal and cellular models


DONEPEZIL:
Neurotrophic and cognitive-enhancing drug

NEUROFIT is a Contract Research Organisation (CRO) specialising in the evaluation of treatments for peripheral and central nervous system disorders.
NEUROFIT offers a long list of in vivo and in vitro validated methods and disease models for drug screening.

  • Neurotrophic support of donepezil in cortical neurons


  • Donepezil: Neurotrophic effect on primary cortical neurons culture

  • Cognitive / memory enhancing effect of Donepezil in different in-vivo assays

  • Donepezil: Reversion of Aging-related cognitive deficit in the T-Maze alternation task in the mouse

  • Donepezil: Reversion of MK-801-induced cognitive deficit in the T-Maze alternation task in the mouse

  • Donepezil: Reversion of Scopolamine-induced cognitive deficit in the T-Maze alternation task in the mouse

  • Donepezil: Reversion of Methyllycaconitine-induced cognitive deficit in the T-Maze alternation task in the mouse


  • Donepezil: Reversion of natural forgetting in the Object Recognition test in the rat


  • Donepezil: Reversion of Scopolamine-induced cognitive deficit in the Object Recognition test in the rat


  • Donepezil: Reversion of Scopolamine-induced cognitive deficit in the Passive avoidance test in the rat


NEUROFIT offers a range of validated in vitro and in vivo screening tests for psychiatry and neurology.

If you need further information, please do not hesitate to contact us, we will reply within few days. Custom protocol

On a regular basis we distribute newsletters with scientific information on our research services. If you wish to receive these, please :